Tag Archive for: DHT blockers

What is DHT & Why Does It Cause Hair Loss?

Dihydrotestosterone is one of the primary causes of hair loss. The Happy Head dermatologists break down the hormone and why it causes hair loss, in addition to how to treat it.

Look into the causes of hair loss, and you’ll inevitably come across DHT, also known as Dihydrotestosterone. Whether you’re male or female, DHT is a likely cause of your thinning hair and bald spots. But what exactly is DHT? And why does it lead to hair loss? 

What is Dihydrotestosterone? 

Dihydrotestosterone (DHT) is a hormone produced in the body as a byproduct of Testosterone. DHT is formed when an enzyme called 5-alpha-reductase converts Testosterone into DHT. DHT plays a significant role in the formation of male characteristics, like facial hair, a deeper voice, and more muscle mass. Unfortunately, DHT is also responsible for hair loss in both men and women. (01)

How Does DHT Cause Hair Loss? 

DHT bonds itself to hair follicles, causing them to shrink. The hair follicles then become smaller and smaller. Eventually, these follicles are unable to grow or hold onto the hair. This process is known as miniaturization, and it’s the primary cause of male and female pattern baldness. (02)

In addition to miniaturization, DHT encourages inflammation in the scalp, which further contributes to hair loss. This inflammation may damage hair follicles and prevent the circulation of nutrients, limiting the scalp’s ability to grow hair. 

An excess of DHT also shortens the anagen (growth) phase of the hair cycle. Typically, hair grows for several years before entering a resting phase, after which it falls out and is replaced by new hair. However, when DHT attaches to hair follicles, it causes hair strands to enter the resting phase earlier than usual, resulting in shorter and thinner hair. (02)

Several other factors can contribute to the overproduction of DHT, including genetics, a person’s age, and hormonal imbalances. Men are also more likely to experience hair loss due to DHT because they have higher testosterone levels than women. However, it’s important to note that women can also experience hair loss due to DHT. 

What are DHT Blockers, and How Do They Work?  

Medications that block DHT’s effects belong to a category of drugs called Dihydrotestosterone blockers (DHT blockers) or 5-alpha-reductase inhibitors. The following are two of the most commonly used DHT blockers: 

DHT blockers work through four primary methods.  (01)

  1. Inhibition of 5-alpha-reductase. DHT blockers work by targeting the production of DHT through the suppression of 5-alpha-reductase. This enzyme converts Testosterone into DHT. Therefore, by blocking this enzyme, DHT levels are reduced.
  2. Decreased DHT levels. By reducing DHT levels, DHT blockers help interrupt hair follicles’ miniaturization process. 
  3. Extended hair growth phase. DHT blockers extend the active phase of hair growth called the anagen phase. DHT blockers prolong the anagen phase, allowing for longer, healthier, and thicker hair growth.
  4. Maintenance of existing hair. When hair loss occurs, protecting the hair that’s present is essential. DHT blockers can help maintain existing hair by preventing further miniaturization of hair follicles. 

For the most part, DHT blockers are more effective for individuals experiencing androgenetic alopecia (pattern hair loss) because this condition is primarily influenced by DHT. Androgenetic alopecia can impact up to 50% of men and women. (03) Other types of hair loss can also be impacted by factors such as nutritional deficiencies or stress; these conditions may not respond as effectively to DHT blockers on their own. In these cases, a multifaceted approach may be required. 

Why are DHT Blockers Prescribed for Hair Loss?  

One of the primary reasons why DHT blockers are prescribed for hair loss is their effectiveness. DHT blockers work! Studies have shown that DHT blockers can significantly reduce hair loss and even promote hair regrowth in some cases. Because DHT is the primary cause of male and female pattern baldness, blocking its production can help to prevent further hair loss. (02)

Another reason why DHT blockers are prescribed for hair loss is their ease of use. Most DHT blockers are available in the form of oral medications, often taken as a once-a-day pill. This makes DHT blockers a convenient option for individuals who don’t want to use topical treatments or undergo more invasive hair restoration procedures.

DHT blockers are also considered to be safe and well-tolerated by most people. Unlike other hair loss treatments, DHT blockers typically do not have significant side effects. Their lack of major side effects makes them a popular choice for a safe and effective hair loss treatment (02)

Is Blocking DHT a Bad Thing? 

Individuals looking into DHT blockers may have questions about whether blocking DHT is a bad thing. The production of DHT is a natural process. Therefore, doesn’t the body need DHT? Is blocking DHT a bad thing? 

Although there is no cut-and-dry answer, blocking DHT is not inherently bad. However, as with any other medication, DHT medication does come with some side effects. These potential side effects must be considered when starting any DHT blocker for hair loss. 

Because DHT plays important roles in the body, including the development of male sexual characteristics and other bodily functions. Therefore, blocking DHT can potentially affect these functions. DHT may cause: (02)

  • Sexual side effects. Some individuals may experience sexual side effects when using DHT blockers. These side effects are generally rare but can occur in a small percentage of users.
  • Hormonal imbalances. DHT blockers may cause alterations in hormone levels, resulting in changes in mood, energy levels, and overall hormonal balance. 
  • Prostate health: Because DHT is involved in the growth and maintenance of the prostate gland, blocking DHT can potentially affect prostate health. It’s crucial to discuss any concerns with a healthcare professional, especially if you have a history of prostate issues.

It’s essential to consult with a healthcare professional before starting any medication or treatment for hair loss. They can provide guidance based on your situation, conduct a thorough evaluation, and discuss DHT blockers’ potential benefits and risks.

Are There Different Ways to Target DHT for Both Men and Women?

While blocking DHT production is a common approach to treating hair loss and works for both men and women, the process may differ. For example, while oral DHT blockers like finasteride are primarily prescribed for treating male pattern baldness, they have been used off-label in some instances of female pattern hair loss. Therefore, women may benefit from DHT blockers for hair loss, but they must also consider the following when utilizing DHT blockers for hair loss. 

Hormonal Effects

DHT blockers can affect hormone levels in the body, potentially leading to hormonal imbalances. Hormonal balance is particularly important for women, and altering hormone levels may have unintended consequences on various bodily functions. (04)

Pregnancy and Breastfeeding

Women who are pregnant or planning to become pregnant and those who are breastfeeding should avoid using DHT blockers. These medications can potentially interfere with fetal development and may have adverse effects on the baby.

While men typically require higher doses of DHT blockers to achieve effectiveness, a little goes a long way for women. This is because men have higher levels of Testosterone, which means they also have higher levels of DHT. In contrast, women have lower Testosterone levels and do not require the same amount of DHT blockers for effective hair loss treatment. Women may also benefit from using a DHT blocker topical, which may have a lower risk of side effects than an oral DHT blocker. 

For women considering oral DHT blockers, it is crucial to consult with a knowledgeable healthcare professional, such as an experienced dermatologist or a hair loss specialist, who can thoroughly evaluate and discuss the potential benefits, risks, and alternatives. They can provide personalized guidance to help make an informed decision about the most appropriate treatment options for hair loss. 

Are DHT Blockers Right for You? 

Happy Head’s proprietary hair growth formula was crafted by the work of our world-renowned hair loss pioneers: Dr. Ben Behnam and Dr. Sean Behnam. Both our founders are widely published in the Journal of American Academy of Dermatology, Journal of Drugs in Dermatology, Journal of Organic Chemistry, Cutis, Expert Opinion in Pharmacotherapy & others. With Happy Head, you know you’re receiving high-quality and well-researched hair loss products with your safety in mind. 

Every individual’s situation is unique. That’s why it’s essential to discuss the use of DHT blockers with a licensed dermatologist who can evaluate your specific situation, provide appropriate guidance, and monitor your progress. Happy Head’s experienced hair loss experts can help you determine the most suitable treatment options. Our experts can also walk you through each medication’s potential risks and side effects. Contact us to develop your individualized hair loss treatment today. 

 

Resources: 

(01) https://www.ncbi.nlm.nih.gov/books/NBK557634/

(02) https://www.ncbi.nlm.nih.gov/books/NBK555930/

(03) https://www.ncbi.nlm.nih.gov/books/NBK430924/

(04) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419033/

Your Comprehensive Guide to Oral Minoxidil

 

If you are dealing with male or female pattern baldness, you’ve probably spent hours researching regrowth options for your hair. And, you probably learned about Minoxidil topical foams and liquid solutions. At Happy Head, we’ve created your comprehensive guide to Oral Minoxidil to answer all of your questions on your search.  Two and five percent Minoxidil is sold at pharmacies and other retailers under the name Rogaine and by prescription in higher doses. You may have even given it a try.  

But, you may not be aware that Minoxidil is also available as a pill.  It’s only available by prescription, and it’s not advertised. A lot of people don’t know about it. But, they should. Some people who don’t respond to topical Minoxidil may have success with oral Minoxidil.  Here’s everything you need to know about oral Minoxidil and how it works.  

Oral Minoxidil Was the First Hair Regrowth Treatment

Back in the ‘70s, Minoxidil was only available in a pill format.  Neither topical foam nor liquid existed.  Here’s the background.  

Minoxidil tablets were initially designed to treat high blood pressure. The medicine is a vasodilator that opens up the blood vessels and relaxes artery walls.  During testing for hypertension, researchers discovered that one of the (not so) adverse effects was hypertrichosis, excessive hair growth. More testing ensued, word spread, and dermatologists began prescribing Minoxidil pills to treat their patients with male and female pattern hair loss.  

In 1987, topical Minoxidil was developed and quickly became the go-to treatment for androgenetic alopecia and other types of hair loss. As topicals took off, the pills fell by the wayside. After all, topicals didn’t require a prescription. Everyone seemed to forget that pills were even an option to treat hair loss.  

Oral Minoxidil Works, But Don’t Ask Anyone to Explain Why

Even today, doctors have yet to learn exactly why Minoxidil works.  One hypothesis is that the medication increases oxygen and blood flow to the hair follicles.  When that happens, the hair growth cycle’s anagen (growth) phase is prolonged and the telogen (resting) phase when your hair falls out is reduced. (01) 

If you take the oral Minoxidil route, the odds of it working are favorable.  In a study of over 19,000 people taking low doses of Minoxidil from .25 to 5 milligrams once or twice per day, 61 to 100 percent of participants saw significant improvement after taking oral Minoxidil. (02)

What’s also interesting is that oral Minoxidil may work when topical Minoxidil doesn’t.  Here’s why.  Many people have an enzyme called sulfotransferase.  Sulfotransferase wakes up your hair follicles and activates Minoxidil.  When people don’t have that enzyme in their hair follicles, they don’t respond to topical Minoxidil.  However, those same people do have sulfotransferase in their livers, which means that people may respond to oral Minoxidil when they don’t respond to topical Minoxidil. (03)

Oral Minoxidil is Used to Treat Many Hair Loss Conditions

Dermatologists prescribe oral Minoxidil to treat various hair loss conditions, most commonly male and female pattern hair loss (androgenetic alopecia).  Oral Minoxidil is also used for other types of non-scarring alopecia, including alopecia areata, traction alopecia, anagen effluvium, and severe telogen effluvium.  

Happy Head's Oral Minoxidil pill that you can take at the highest strength for the best hair growth results.

Here are the Reasons Why You May Want to Consider Oral Minoxidil

Why do people choose the oral route if topical Minoxidil is also an option?  There are a few reasons. Topical Rogaine can sometimes contain propylene glycol, which can be irritating. Removing the ingredient can help, but people still sometimes develop a rash or an allergy.  In this case, oral Minoxidil may be a better option. Pills are also an option if you’ve already tried topical Minoxidil for at least six months and the growth isn’t meeting expectations. Lastly, some people find that topical Minoxidil dries their hair changing the texture and causing breakage. Oral Minoxidil alleviates the issue.  

1. Minimal Side Effects

Taking an oral medication designed for hypertension can seem scary. You don’t want to trade off one problem for another, especially when the issue you are trying to address is cosmetic.  Not to worry. Minoxidil doses prescribed for hair loss are so low side effects are rare.  Here’s what people have experienced:

Hypertrichosis – When oral Minoxidil makes your hair grow, it doesn’t distinguish between the hair on your head, body, or face.  It can make all of your hair grow.  Yes, it’s an annoying side effect, but it can easily be managed.  Men usually aren’t as bothered as women, but hair removal (ironic, right?) and dosage adjustments are quick fixes if necessary.  

Shedding – Yes, it’s true that just like topical Minoxidil, oral Minoxidil can also cause temporary shedding when first using the medicine.  The reason why is that Minoxidil adjusts your hair’s growth cycle.  If shedding occurs, it’s best to continue taking your oral Minoxidil as prescribed.  Shedding usually happens within the first six weeks and resolves after four weeks.   

Low Blood Pressure – Minoxidil is prescribed at much higher doses (10-40 milligrams) to control high blood pressure.  Even though much lower doses are used to treat male and female pattern baldness,  it is possible, yet not typical, for people to experience dizziness due to low blood pressure.  If that happens, contact your dermatologist, who can adjust your dosage.  

Other side effects may include swollen ankles, fluid retention, headaches, and a fast heart rate.  Keep in mind that less than two percent of people using oral Minoxidil experience side effects, so the likelihood that you will have these or other symptoms are low. (04) 

2. Keep Track of Your Blood Pressure and Heart Rate

Although it’s not likely that you will experience side effects from taking oral Minoxidil, some people do experience fluctuations in blood pressure, even at low doses. As a precaution, purchasing and using a home blood pressure monitor is a good idea.  Take readings before you begin the medication and check again once each week. It’s a good idea to track the readings, keep a chart, and bring the results to appointments.

3. It’s Inexpensive

If you have health insurance with a prescription plan, oral Minoxidil is usually covered. If not, the retail cost is low. Depending upon where you fill your prescriptions, a 30-day supply of oral Minoxidil can cost less than seventy-five cents per pill.  

4. It’s Easy to Take

Topical Minoxidil works well for many people without any issues. However, some people find that topical Minoxidil can cause irritation or be difficult to apply. Minoxidil works on the scalp, but the foam sometimes gets stuck in the hair.  Liquids can be runny.  Oral Minoxidil only requires one or two daily low-dose pills without any hassle or mess.  

5. Low Doses are Available

As mentioned, the amount of Minoxidil necessary to treat male or female pattern baldness is significantly less than what’s required to treat high blood pressure. Whereas 20 to 40 milligrams are prescribed to treat hypertension, a range of .25 to 1.25 milligrams is often prescribed for androgenetic alopecia.   If necessary, a 2.5-milligram tablet can easily be cut into quarters or halves with a pill cutter.  Men sometimes take higher doses than women.  

6. Can Be Combined with Other Hair Loss Medications

Always check with your doctor before combining medications, especially if you use other medicines that affect your blood pressure. That said, it’s generally safe to take oral Minoxidil with DHT blockers such Finasteride or Dutasteride like in our SuperCapsule™. Oral and topical medications can be combined as well. Research indicates that using Minoxidil and DHT blockers simultaneously leads to effective results. (05)

7. Take it Under a Doctor’s Care

You may not be aware of situations when it’s not safe to take oral Minoxidil. That’s why it’s important to have a doctor supervising your treatment protocol.  You want to avoid aggravating drug allergies, liver conditions, adrenaline dysfunction, heart conditions, and other health issues.

8. It Isn’t a Quick Fix or a Hair Loss Cure

Like topical Minoxidil, oral Minoxidil is a long-term commitment. Once you stop taking Minoxidil pills, you can lose new hair growth.  That’s why it’s important to use the medication under the supervision of a licensed dermatologist and be consistent. 

9. Be Sure to Keep Your Follow-up Appointments

If you begin an oral Minoxidil protocol, it’s important that you follow up with your provider as he or she recommends.  Initially, you may need to schedule appointments every three months.  Once your dose is established and stable, you may only need to see your doctor every six months to a year.  

Now that you know the benefits of oral Minoxidil, you may wonder if it’s right for you.  That’s where we come in.  Thanks to telemedicine, you can consult with one of our board-certified dermatologists without ever visiting an office or pharmacy. We’ll review your medical history and get a better understanding of the type of hair loss you’re experiencing. If oral Minoxidil is the way to go, we’ll ship your prescription in discreet packaging directly to your door.  

Resources:

(01) https://www.aad.org/dw/dw-insights-and-inquiries/archive/2022/low-dose-oral-minoxidil-alopecia

(02) https://www.aad.org/dw/dw-insights-and-inquiries/archive/2022/low-dose-oral-minoxidil-alopecia

(03) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691938/

(04) https://pubmed.ncbi.nlm.nih.gov/33639244/

(05) https://cosmoderma.org/combination-therapy-with-oral-minoxidil-and-dutasteride-in-the-treatment-of-male-patterned-baldness-a-case-report/

 

Dealing with Hair Loss? Get These Hormones Under Control.

Here’s a fun fact: hormonal imbalances are the leading cause of hair loss.  At least 50 percent of men are affected by the age of 50. (01)  Ladies, this is true for you too.  Those chemicals that send messages to your organs, skin, muscles, and other tissues are pretty powerful.  They rule your emotions, your weight, your sleep patterns, and, yes, your hair.  If your hairline is receding, or you’re starting to see bald patches on the crown of your head, it may be a sign that you need to get those hormones under control.  Not sure how?  Here are some tips and tricks to help.  

Hormonal Hair Loss Triggers

Before we get into the nitty-gritty, let’s talk about the different types of hormonal hair loss.  Not all hair loss due to hormonal imbalances is the same.  Some hair loss is short-term. Once balance is restored, your hair will grow back.  Other types are a bit more challenging to manage.  In this case, medication can help stop your hair loss and jump-start the growth process.  Fortunately, great progress has been made researching and developing medications designed to treat hair loss due to hormonal imbalances.  Many effective oral and topical options are now available.  So, what hormones cause temporary hair loss, and which create more long-term issues?

Testosterone

We’ll start with testosterone.  Testosterone is the hormone that stimulates the development of male sexual characteristics.  Testosterone affects men’s sex drive and sperm production.  It also plays a role in bone and muscle mass, fat storage, blood cell production, and mood.  Women also produce testosterone, but in much smaller amounts.  

Typically, about ten percent of testosterone in men and women converts to an androgen called dihydrotestosterone (DHT) due to an enzyme called 5-alpha reductase (5-AR).  Once DHT flows through your bloodstream, DHT attaches to the receptors on your hair follicles.  The hair follicles then shrink, making your hair thin and eventually fall out, causing what’s known as male or female pattern hair loss.  

Solution:  Successfully treating male or female pattern hair loss often takes a multi-faceted approach.  Enlarging the hair follicles while blocking the testosterone from converting to DHT is usually the best strategy.  It can, however, take some trial to determine which medications and strengths are most effective for each person.  Minoxidil is often used to open the follicles.  Commonly used DHT blockers include Finasteride, Dutasteride, and Spironolactone.  All of these medications are available in oral or topical formulas.  Many people prefer topicals since they eliminate the risk of systemic side effects.  

Cortisol 

Who isn’t stressed out these days?  Pressure at work, rising costs, and keeping peace at home can be a lot to handle.  When you get stressed out, your body generates extra cortisol.  Cortisol is produced and released in your adrenal glands which are located on top of your kidneys.  Its job as a steroid hormone is to tell your body, ”Hey, you need to chill out!” When your cortisol level gets high, it can reduce the synthesis and speed up the breakdown of hyaluronic acid and proteoglycans in your scalp.  The increase interrupts your hair’s growth cycle, which can lead to hair loss.

Solution:  Breathe.  Hair loss due to stress is usually temporary.  Your hair will grow back on its own once the stressors are gone.  Head outside for a walk, sign-up for a yoga class, or download a meditation app to listen to before bed.  If the usual tricks for restoring calm in your life don’t work, seeking help from a counselor or therapist may be the way to go.  

Triiodothyronine (T3) & Thyroxine (T4)

T3 and T4 are hormones produced in the thyroid gland.  They control how your body uses energy and help regulate many functions from your metabolism to brain development.  T3 and T4 are the markers typically used to help diagnose thyroid disorders.  Too high or too low can be signs of hyper or hypothyroidism.  Both hyperthyroidism and hypothyroidism can lead to hair loss with specific patterns.  People who lose their hair due to thyroid issues usually see thinning over the entire scalp.  

Solution:  Treating the thyroid disorder usually leads to regrowth over several months.  If you think your hair loss may be thyroid related, you’ll need an appointment with an endocrinologist.  Once your thyroid is treated, your hair will slowly grow back.   

Estrogen and Progesterone 

Decreases in estrogen and progesterone levels have been proven to affect women’s hair growth cycles. (02)  That’s why women tend to see their hair thinning or shedding after childbirth or during menopause.  During menopause, a decrease in these hormones also causes an increase in androgens that produce DHT.  DHT conversion happens for women as it does for men, resulting in female pattern hair loss.  Hair lost after childbirth usually resolves itself and grows back over time.  Hair loss due to menopause requires treatment.

Solution:  If you’ve recently had a baby or are nearing menopause age, visit your dermatologist for a consultation and diagnosis.  Postpartum hair loss and female pattern baldness can usually be diagnosed through a visual exam.  There are very specific patterns of hair loss.  You don’t want to assume that your hair loss is hormone-related, just in case another cause requires different treatment.   

How to Treat Hormonal Hair Loss

If your hair loss is due to hormones, treatment options will be based on your condition.  In some cases, your hair will grow back on its own.  Other cases will require treatment.  Here’s an idea of the different types available: 

Minoxidil

Minoxidil, a popular hair loss medication, is sold over the counter and in stronger doses by prescription.  It helps enlarge your hair follicles and allows healthy hair to grow.  It’s best to have a board-certified dermatologist monitor your Minoxidil use.  The reason why is because the medication must be continued once you start using it.  If you discontinue Minoxidil, the hair you grow while using the medication can fall out.  

DHT Blockers

When male or female pattern hair loss is an issue, preventing testosterone from converting to DHT is one of the most effective ways to stop thinning and shedding.  A few different types are available, including Finasteride, Dutasteride, and Spironolactone for women.  Prescription DHT blockers are available in pill or topical formulas.  Each have pros and cons, so it’s important to work with your dermatologist to determine which medication and formula is best for you.  

Supplements

Supplements alone won’t regrow your hair, but they can help treat the root cause of your hair loss.  Iron and vitamin D deficiencies are common among people with hair loss due to hormonal imbalances.  Collagen, probiotics, and other supplements can also help strengthen your hair and scalp.

Thickening Shampoo & Conditioner

The right shampoo and conditioner can help make your hair thicker, shinier, and healthier.  Look for products infused with collagen, saw palmetto, keratin, biotin, and other ingredients that have been proven to support hair growth.

 

Whether you’re 15, 50, or 70, dealing with hormone imbalances can be a nuisance.  However, thanks to research and technology, you have more reliable and accessible options than ever to deal with associated hair loss.  You don’t even have to leave your sofa.  Simply answer a short hair loss questionnaire and our licensed dermatologist will review your case.  If you are a candidate for hormone-induced hair loss, we can make recommendations and deliver customized prescription medications directly to you.  Want to learn more?  Get in touch with us for an evaluation and personalized treatment plan.  

 

Resources:

(01) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817427/

(02) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432488/

 

Is Minoxidil (Rogaine) Safe for Women?

Young woman with curly hair looking at herself in the mirror and combing hair with hand, photographed from behind

You may be familiar with Minoxidil that’s used to treat thinning hair and bald spots. The medication was initially tested, marketed, and FDA-approved for men with male pattern baldness. If you’re a woman experiencing hair loss, you may wonder if Minoxidil is safe and effective for you too. After all, Minoxidil is available under the brand name Rogaine over the counter at most big box retailers and pharmacies. It’s easy to buy and use.  

Dermatologists Often Recommend Minoxidil to Their Female Patients

Minoxidil is safe, and it’s the medication most often recommended to women by dermatologists to treat their hair loss conditions. Before you run to the store, though, there are a few things you should know.  

Minoxidil Is FDA Approved for Women

If you’re considering using Minoxidil to treat your hair loss, you’ll be happy to know that the five percent topical foam and solution was FDA-approved for women in 2014. The medication was used off-label for women before it was approved. Why is FDA approval notable? Because it means that the manufacturer proved that its product is safe and effective for its intended use. FDA approval also means the product is manufactured to federal quality standards.  

Higher Doses of Minoxidil are Available by Prescription

Oral Minoxidil and topical Minoxidil doses above five percent are available to women but only off-label by prescription. Don’t be concerned about using prescription medication off-label, though. The FDA knows that medical providers do that. Off-label means that dermatologists may prescribe a drug for use that isn’t approved when the provider determines that the medication is medically appropriate.  

Minoxidil Is Used to Treat Female Pattern Baldness and Other Hair Loss Conditions

Minoxidil is most often recommended and prescribed to treat androgenetic alopecia, commonly known as female pattern baldness. Female pattern baldness occurs in women who are genetically predisposed to hair loss. When women experience this condition, they typically see hair loss along their parts first. Over time, the part widens as the hair in the area continues to thin and fall out. While men who experience male pattern baldness can lose all of their hair over time, women typically don’t. Women are more likely to see diffuse thinning on the crown of their heads.  

Minoxidil is often prescribed for other hair loss conditions as well. Dermatologists often recommend Minoxidil to their female patients with alopecia areata, frontal fibrosing alopecia, lichen planopilaris, and other types of alopecia.

Minoxidil is Available to Women in Different Forms & Doses

Liquid & Foam Rogaine

If you go to the store, you’ll find foam and liquid Minoxidil in two and five-percent formulas. Minoxidil is the same as Rogaine. You may also find generic store brands of Minoxidil under names such as Equate and Kirkland Hair Regrowth Treatment, which contain the same active ingredients.  

Initially, only two percent formulas were marketed for women. However, research indicates that higher doses are more effective for treating female pattern hair loss. Although both two and five percent solutions increased hair growth, the five percent demonstrated statistical superiority over the two percent. (01) When choosing between the liquid and foam, you may want to consider foam that does not contain propylene glycol which can be an irritant to some women. 

Oral Minoxidil

Oral Minoxidil is an alternative to topical and is available by prescription.  The medication is effective in regrowing hair in women with female pattern baldness. (02)  Oral Minoxidil was initially tested in higher doses to treat high blood pressure.  When used to treat genetic hair loss, much lower doses are prescribed.   

Minoxidil With DHT Blockers

The most effective treatments attack hair loss from different angles. Women often use Minoxidil simultaneously with DHT blockers such as Finasteride or Spironolactone. Minoxidil enlarges the hair follicles, while Finasteride or Spironolactone prevents Testosterone from converting to DHT. When DHT is blocked, it can’t bind to the receptors in your hair follicle so your hair won’t be at risk.  

Customized Topical Minoxidil Formulas

Treatments for female pattern baldness may differ from woman to woman. What works for one may not work for another, which is why customized formulas are often best. The most effective treatments attack hair loss from different angles. A benefit of customized formulas is that Minoxidil can be prescribed up to 10 percent, which is significantly higher than what’s available over the counter. Retinol can be added to increase absorption, and cortisone can be added if necessary to prevent irritation from higher concentrations of Minoxidil. Many women also like the convenience of having all of the hair loss medications they need to be compounded into one formula rather than having to take or use multiple medications.       

Minoxidil Side Effects are Usually Minimal

Minoxidil users usually don’t experience many side effects. Topicals can cause some redness, flaking, and irritation. However, eliminating propylene glycol usually resolves the issue. Oral Minoxidil was originally tested and marketed to treat high blood pressure. Because oral medications are systemic, side effects such as a fluctuating heart rate are possible. Side effects are rare, though. Doses of oral Minoxidil prescribed for hair loss are typically significantly lower than for high blood pressure.  

Minoxidil Can Cause Initial Shedding

If you’ve been researching Minoxidil for your hair loss, you may have heard about the “dread shed” that can occur when first using Minoxidil.  Yes, some women find that they lose more hair at first. The reason why is because Minoxidil speeds up your hair’s growth cycle. The resting phase occurs faster than it otherwise would. Everyone doesn’t experience an increase in shedding. However, If you do shed initially, don’t panic. Your hair’s growth cycle will regulate within a few weeks.  

Trying Minoxidil is the Best Way to Determine Whether it Will Work for You

It would be nice if there were a way to know whether Minoxidil will help regrow your hair. A response test has been designed and marketed to do just that. The test measures the amount of sulfotransferase enzyme activity in plucked hair follicles to predict whether or not Minoxidil will be effective. Research indicates that the sulfotransferase activity predicts treatment response with 93 percent sensitivity and 83 percent specificity. (03) There’s a catch, though.  

The test will only help determine if women will respond to two or five percent topical Minoxidil. The test does not indicate whether or not women will potentially respond to higher topical dosages or to oral Minoxidil. It also does not indicate whether Minoxidil will be effective when used with a DHT blocker such as Finasteride or Spironolactone. The best way to know if Minoxidil will work is by trial. It typically takes six to twelve months to see results. 

If you have been diagnosed with female pattern baldness and are thinking about trying Minoxidil, here’s the takeaway. Minoxidil is safe for women to use and has been proven to be an effective treatment for many. Minoxidil often works best with Finasteride, Spironolactone, or another DHT blocker.  A topical with a percentage higher than five or oral Minoxidil will require a prescription. If you have more questions about whether Minoxidil is right for you, Happy Head’s board-certified dermatologists can help. Contact us and our hair growth experts will help select the best solution for you, without a visit to the doctor’s office. 

Resources:

(01) https://pubmed.ncbi.nlm.nih.gov/15034503/

(02) https://pubmed.ncbi.nlm.nih.gov/32851744/

(03) https://pubmed.ncbi.nlm.nih.gov/24773771/

 

Your Holiday Hair Loss Guide

‘Tis the season for parties, spending time with family and friends, and traditional holiday meals.  It’s the most wonderful time of the year, right?  Well, not for everyone.  Some people dealing with hair loss find that the holidays bring a whole new level of angst about their appearance.  You may plan to visit friends and family members you haven’t seen since last year, or even longer.  And, for sure, you’ll end up in some of those pictures posted on Facebook or Instagram.  Finding the perfect outfit is one thing, but trying to camouflage your thinning or balding hair is a whole different story.  Is that even possible?  Before you RSVP “no” to your next invite and pull out the flannels, take a deep breath and check out the following tips.  You can find joy during the holidays, even when battling male or female pattern baldness or another type of alopecia.     

Give Yourself a Break

It can be hard to accept that your looks are changing.  You may not look like you did last year.  Or, even like you did a few months ago.  That’s okay.  It’s time to stop comparing the new you to the old you.  You’re probably harsher on yourself than others would be.  When you see balding, thinning hair in the mirror, others may not even notice or care.  They’re more likely to remember the funny story or joke you told.  It’s true.  While someone may remember what you look like, research indicates that others are more likely to remember how you make them feel when you’re around. (01)  Do the best you can to turn off your inner critic, and remember that how you interact with others makes you uniquely attractive, not your hair.   

Go Out and Stay Involved

Arg.  Every time you look in the mirror, it seems like there’s more hair missing.  You’re grumpy and don’t feel like talking to or seeing anyone.  How can you go out looking like that?  So, instead of going to your friend’s holiday party, you put on your baggiest sweats and start binge-watching Dahmer while downing a pizza.  Good idea, right?  Nope.  According to the American Psychological Association, that’s the worst thing you can do. (02)  Social isolation can not only affect your sleep, but also cause depression and lower your immunity.  It can have long-lasting psychological effects.  You’re better off rallying and forcing yourself to go to the party.  Socializing will get your mind off your hair loss, even if it’s for a bit.  Talking to other people will also help you feel less alone and put you in a better mood.  

De-stress

Controlling stress is important for everyone’s health and well-being.  It’s especially important if you’re dealing with hair loss.  If you’re already experiencing male or female pattern baldness or another type of alopecia, you definitely do not want stress-induced hair loss too.  The holidays are a particularly tricky time for managing stress, though.  Family drama and searching for the perfect gift when there’s limited inventory can push anyone over the edge.  The good news is that there are ways to manage.  Here are some ways to help you de-stress:

1. Get enough exercise

Get outside or to the gym if your hair loss is giving you the holiday blues.  Physical activity not only makes your body feel better, but it’s also good for your mind.  Exercising may help increase your endorphins, putting you in a better mood after.  Bonus is that exercise increases the blood flow to your scalp.  This means that more oxygen and nutrients are helping kick your hair’s growth phase into full gear.  

2. Sleep

Not only does sleep calm and restore your body, but it can also help hair growth.  Your body produces melatonin primarily at night.  Some studies even suggest that melatonin supplementation helps promote hair growth among people with male and female pattern hair loss. (03)

3. Pamper yourself

We’re going to put this out there.  Sometimes the best way to relieve stress is to pamper yourself.  Whether that’s a massage, listening to holiday music, or reading a book doesn’t matter.  Whatever makes you let go and relax works.  

4. Set a budget and stick to it

It’s easy to get burdened with extra debt and associated worries about how you will pay for all of those gifts during the holidays.  Prevent that from happening by setting a budget and making sure that you stick to it.  

5. Set a schedule

So much to do and so little time.  The holidays will be here before you know it.  How are you going to get everything done in time?  Writing your to-dos down will help you manage your time and expectations.  You’ll find time for the most important tasks, and you might even schedule some downtime.  

6. Accept imperfections

Acknowledge that the holiday may not go as planned, and remember that imperfections are healthy and normal

7. Remember what’s important

Keeping perspective when you’re stuck in a long line or annoyed with a relative can go a long way toward keeping you calm.  Will another 10 minutes really change your day?  Does it matter that your sister wants to bring stuffing instead of pie?  

8. Be patient

You can’t change others’ behavior, but you can choose how you respond.   If a situation gets tense, take a few deep breaths and focus on an appropriate response versus a quick reaction.  

Get a New Do

Maybe you’ve been letting your hair grow out, hoping to cover the balding or thinning areas.  Or, perhaps you’ve been afraid to cut your hair because you’re worried it might not grow back.  The holidays are the perfect time to visit your stylist and try out a new look.  Remember, androgenetic alopecia is the most common form of hair loss.  Millions of people are experiencing the same condition you are.  Your barber or stylist probably has a few tricks to help you get party-ready. 

Consider Treatment Options for Your Hair Loss

Accepting that your hair is thinning or balding isn’t easy, especially when you’re active and social.  The good news is that you don’t have to accept your fate.  The best way to deal with hair loss is by fighting it.  Fortunately, medications with high efficacy have been tested and are available.  

The most effective hair loss treatments are vasodilators and DHT blockers. Minoxidil is a vasodilator, which increases blood flow to your scalp and hair follicles.  More oxygen enlarges the hair follicles allowing existing hair to remain stable and healthy.  It also allows new hair to emerge.  

Prescription DHT blockers serve a different purpose.  Male and female pattern baldness occurs when testosterone converts to Dihydrotestosterone (DHT).  DHT is what attacks your hair follicles and makes your hair fall out.  DHT blockers prevent the conversion.  The most commonly prescribed DHT blockers are Finasteride, Dutasteride, and Spironolactone.  Because Minoxidil and  DHT blockers treat hair loss from different angles, the two medications are often used simultaneously.  Retinol may be prescribed as well to increase the absorption of the other medications.  If irritation is a concern, low doses of cortisone can be added.  All-in-one topical formulas prevent side effects and can be more convenient than oral medications.

Research Alternative Hair Loss Solutions

Prescription medications are a great choice for many people; however, there are alternative hair loss solutions that can help camouflage your hair loss and give your confidence a boost.

Hairpieces

Looking for a quick fix?  Today’s hair pieces come in a wide variety of materials, textures and styles.  Testing them out can be fun and can give you a fresh new look that will make you ready to rock the room.

Scalp Concealer

Some people with male and female pattern baldness swear by cover-up sprays and powders.  The tint of color is just enough to conceal balding or thinning areas.  A wide variety of colors are available to make a good color match, and the concealers are designed to be long-lasting.  

Hair Transplants

If your hair loss is stressing you out and you don’t have the patience to wait for other treatments to work, you can always treat yourself to a hair transplant.  Hair transplants are surgical procedures where healthy hair is moved from the back of your head to the front.  Hair transplant practices have evolved over the years and produce a more natural look than ever before.  Transplants can be pricey and aren’t usually covered by insurance since they’re considered cosmetic procedures.

Talk About It

It’s normal to be upset about losing your hair, but if your hair loss is starting to interfere with your holiday plans, you may need a support system.  Using a therapist, meeting up with a group locally, or even joining a Facebook group for people with alopecia can help you feel less alone and develop coping skills.  Finding a way to talk about your feelings may be one of the best gifts you give yourself this holiday season.

If the idea of stopping your hair loss and regrowing your hair brings you happiness and joy, what are you waiting for?  It’s time to get more information on customized hair growth solutions.  The best part about our prescription-grade solutions is that ingredients can be added or removed based on your particular needs.  Get started now and check out our special edition holiday pack.

Resources:

(01) https://pubmed.ncbi.nlm.nih.gov/25750481/

(02) https://www.uvu.edu/news/2020/04/04072020_isolation_mental_health.html#:~:text=The%20American%20Psychological%20Association%20reports,have%20long%2Dlasting%20psychological%20impact.

(03) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681103/