Happy Head

Oral Spironolactone for Hair Loss

$199 every 4 months (4 month supply) (Cancel anytime)

What is Oral Spironolactone for female hair loss?

Oral spironolactone is an FDA approved medication used to treat high blood pressure and has been used off-label for treating female pattern hair loss and adult hormonal acne. It is a testosterone blocker that prevents DHT formation, which is good, since DHT has been shown to cause hair loss.  

Spironolactone is typically taken once a day, and results are seen in about 6 months. It is the most commonly used oral medication for female pattern hair loss and is backed up by many clinical studies

In a UCLA study assessing the effective of oral spironolactone for hair loss, 74.3% of patients receiving spironolactone reported stabilization or improvement of hair loss.1 In another study of oral anti-androgen blockers that included spironolactone, 88% of female patients saw either an improvement of their female pattern hair loss or no progression of the disease.2 

Spironolactone can be used concurrently with other medications, such as topical minoxidil, antibiotics or birth control medications. Spironolactone is a diuretic, which means that it may help you make more urine. While rare, the most common side effects may include a change in blood pressure, such as dizziness or lightheadedness, breast tenderness, breast enlargement, irregular periods or spotting between periods. Spironolactone may increase potassium levels in your body, so patients should avoid foods that are high in potassium, such as bananas, coconut water or avocados. Patients should avoid pregnancy on this medication. Spironolactone is a prescription medication, so a medical consultation is required. Happy Head includes the medical consultation for free!  Just fill out the form online and your doctor will review your case!

How Does Oral Spironolactone Work?

Spironolactone helps female pattern hair loss by competing with androgens and preventing them from binding to receptors. In other words, it blocks testosterone binding to testosterone receptors. Testosterone is the hormone responsible for hair thinning. Typically, testosterone is converted into another hormone called dihydrotestosterone, also known as DHT. DHT is responsible for shrinking hair follicles and causing thinning and baldness. Spironolactone competes with testosterone to bind to the testosterone receptors. By doing so, it prevents testosterone from converting into DHT. By effectively reducing the levels of DHT, spironolactone helps to combat female pattern hair loss. 


Spironolactone 75mg, taken once a day orally

How Does Happy Head Work?

Since spironolactone is a prescription medication, it requires a doctor’s consultation and prescription. With Happy Head, the doctor’s consultation is free, and included when you purchase of oral spironolactone. Simply fill out the short medical survey, and a physician will review your medical history and determine your eligibility for our prescription medication. Once approved, the prescription is written, sent electronically to the pharmacy and the medication is shipped out to you in discreet packaging with FedEx 2-day delivery. You will also receive free continuous support from our physicians in case there are any questions or issues.  

Disclaimer & Caution:

Results may vary per patient. Results are not guaranteed. Women who may become pregnant or who are pregnant or breastfeeding should avoid taking spironolactone. Some side effects may include dizziness or lightheadedness, breast tenderness, breast enlargement, irregular periods, spotting between periods or elevated potassium levels. Please see the Drug Safety Information below for more information.

  1. Famenini Shannon, BS, Slaught Christa, BS, Duan Lewei, MS, and Goh Carolyn, MD. Demographics of women with female pattern hair loss and the effectiveness of spironolactone therapy, J Am Acad Dermatol. 2015 Oct; 73(4): 705–706.
  2. Sinclair R, Wewerinke M, Jolley D. Treatment of female pattern hair loss with oral antiandrogens. Br J Dermatol. 2005;152(3):466–73)